Does Synthetic Urine Work For eScreen? (What to Expect)

A doctor inspecting a jar of urine

If your employer is using the eScreen’s service to test employees for drug abuse, it’s perfectly understandable to ask if synthetic urine will help you pass a drug test like eScreen.

I’ve read and researched every possible resource on how eScreen performs its tests and what you can expect.

Let’s see if synthetic urine will help you with this.

Quick Summary

  • If synthetic urine has the same chemical makeup as human urine, then the lab shouldn’t be able to detect it.
  • A typical urine analysis cannot tell the difference between a sample of real urine and fake pee because both samples have similar characteristics.
  • Although employers often insist on a particular panel drug test, synthetic urine can pass all these tests.

Synthetic Urine and eScreen

A jar full of urine ready for drug testSynthetic urine, also known as fake urine, is a substance that imitates real urine. The first thing to know about it is that there are two forms of synthetic urine: powdered and liquid [1].

The powdered synthetic urine is dehydrated urine, which you mix with water to create a liquid form.

The liquid synthetic urine is an already-mixed solution of powdered urine, water, and other ingredients. 

People often use synthetic urine to avoid the detection of drugs in their system when they are being tested.

While most urine drug tests look for specific drugs, eScreen’s tests are different. eScreen’s drug tests are designed to look for the presence of certain enzymes and chemicals that are only found in human urine.

“Synthetic urine (SU), which was primarily utilized by drug testing laboratories as a matrix for quality control preparations, is now commercially sold and can be used to “fool” a positive drug test.”
Marisol S Castagneto, Forensic Toxicology

If the levels of these drugs or metabolites are below the cutoff level, then the urine drug test is considered negative.

However, the test is considered positive if the levels are above the cutoff level.

eScreen’s cutoff levels are in line with those set by the Substance Abuse and Mental Health Services Administration (SAMHSA) [2].

Synthetic urine can pass all of eScreen’s drug tests because it has the same chemical makeup as real human urine, making it in line with SAMHSA’s standards. 

What is eScreen?

A woman holding a test tube filled with urine in a laboratoryeScreen is a drug testing company that provides lab-based urine drug tests for employers. Employers use eScreen to test for drugs like marijuana, cocaine, opiates, and amphetamines [3]

eScreen’s urine drug tests are performed by a certified laboratory. 

The lab will test for drugs in the urine sample and report the results to the employer.

If the lab detects the presence of drugs in the sample, the employer will be notified and may take action against the employee.

5 Synthetic Urine Ingredients

Different laboratory equipment and containers filled with urine

Most synthetic urine contains five primary ingredients that must exactly replicate the composition of human urine.

1. pH Level

pH level is a measure of how acidic or basic something is. The ideal pH level for urine is between 4.6 and 8.0. Urine with a pH level outside this range is considered abnormal and could result in a false positive urine test.

2. Temperature

An image of a person getting a sample of urine from a jarTemperature is another critical factor that must be considered when using fake pee. The eScreen lab will reject urine that is too cold or too hot.

Maintaining the synthetic urine’s temperature between 32 and 38 degrees Celsius is key.

Luckily these synthetic urine kits are frequently sold online with heating pads to keep the urine warm at body temperature.

3. Creatinine Level

Creatinine is a waste product the body generates due to muscular decay. Creatinine levels in the urine are one method to assess kidney health.

Chemists add tiny amounts of certain chemicals to make fake urine seem like it came straight from a person’s body.

This is done so that urine drug tests won’t be falsely positive due to low creatinine levels.

4. Color

The color of urine can range from pale yellow to dark amber, depending on the person’s fluid intake and other factors.

When using fake urine, choosing a product with the correct color is essential.

This will ensure that your sample does not stand out and raise suspicion from eScreen lab technicians.

5. Urea/Uric Acid

Urea or uric acid is another waste product that is produced by the body and excreted in the urine. It is added to fake pee to give it the same specific gravity as actual urine.

Is eScreen Accurate for Urine Drug Testing?

In the realm of urine drug testing, many employers are opting for rapid drug testing kits over traditional laboratory testing methods due to their practicality. One such popular choice among employers in the United States is the eScreen Drug Test. Renowned for its reliability, practicality, and accuracy, the eScreen Drug Test has gained significant recognition.

According to available resources, the eScreen Drug Test boasts an impressive accuracy level of 99%. This accuracy level rivals that of laboratory-based drug screening, making it a highly reliable option for employers seeking precise and trustworthy results.

To ensure accuracy, the eScreen Drug Test incorporates various components, including a quantitative drug test to measure drug concentrations accurately. Additionally, it utilizes a temperature strip to monitor the temperature of the urine sample, further enhancing the accuracy and integrity of the testing process.

In conclusion, employers trust the eScreen Drug Test due to its exceptional accuracy, which stands at an impressive 99%. Its advanced features, such as quantitative drug testing and temperature monitoring, contribute to its reliability and practicality, positioning it as a preferred choice for accurate urine drug testing.

Can an eScreen Detect Synthetic Urine?

A woman holding a jar of urine while showing a thumbs upNo, eScreen can’t detect synthetic urine because their laboratories do not look for the genetic makeup of the urine. 

I’ve personally used both powdered and liquid form synthetic urine to pass an eScreen drug test, and they both have worked perfectly. 

Even if your employers asked for an additional specific panel drug test (5, 9, or 10), you could quickly pass all these tests with synthetic urine.


What Is the Difference Between a Drug Test and a Drug Screen?

The difference between a drug test and a drug screen is that a drug test is more thorough and accurate than a drug screening, but a drug screening yield results faster and at a lower cost.

Does Synthetic Urine Expire?

Yes, synthetic urine does expire. The expiration date is generally about one year from the manufacture date, but it can vary depending on the brand. 

How Long Does It Take for an eScreen Drug Test to Come Back?

It takes 2 to 3 days for an eScreen drug test to come back. However, if it is an eScreen 5 Panel Drug Test, it would take 15 minutes. 

Should You Use Synthetic Urine for eScreen?

Synthetic urine is an excellent option if you face a drug test from eScreen. If you are looking to buy synthetic urine, I suggest you check out Quick Fix Synthetic Urine

The urea, creatinine, pH, specific gravity, and chemical balance in Quick Fix’s urine are all perfect replicas of human urine, making it easier for you for eScreen.

Not only is the fake pee designed to be unisex, but it is also safe to use with all drug tests, including those done via urine drug screens.

I’ve tried many products over the years, but none have worked as well for me as the Quick Fix synthetic urine kit. 



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