OxyContin Withdrawal Symptoms (3 Types of Indications)

A OxyContin drug pouring out of the container

OxyContin carries a high risk of tolerance, dependence, and eventual drug abuse. Although one of the most potent opioids available, its time-release formula makes it suitable for long-term pain management.

The OxyContin detox process can be uncomfortable due to the drug’s strength and the following withdrawal symptoms.

In this article, I will share the results of my extensive research on opioid and OxyContin addiction. I will focus on the symptoms of OxyContin withdrawal and offer strategies for managing them.

Quick Summary

  • OxyContin withdrawal symptoms are like those of heroin withdrawal and can include flu-like symptoms.
  • The initial symptoms of withdrawal may include muscle and joint pain, nausea, desire for the substance, irritability, headaches, and restlessness.
  • The duration of opioid withdrawal differs based on whether the opioids are short-acting or long-acting.

What Is OxyContin?

OxyContin tablets on a red backgroundOxyContin is a medication that contains oxycodone, a synthetic opioid. Doctors prescribe it, and it is a popular opioid in the United States, with millions of prescriptions written every year. Unfortunately, this has led to OxyContin misuse.

OxyContin is a powerful narcotic opioid classified as a Schedule II controlled substance because of its high potential for abuse [1] [2]. Despite the risk, it is commonly prescribed to alleviate severe pain for medicinal purposes. 

It is effective because it can interrupt pain signals, promote relaxation, and trigger endorphins, which can improve overall well-being.

Although OxyContin is a safe and effective treatment for chronic pain when prescribed for legitimate reasons, it is still possible for users to develop tolerance and dependence on the drug even if they adhere to the recommended dosage. 

The FDA cautions in the OxyContin prescribing information that normal use could lead to OxyContin addiction and dependency [3].

Even if used as instructed by a doctor, chronic use of substances can lead to dependence. Essentially, a person may need the drug to function normally. Severe addiction can result in continued compulsive drug use to avoid withdrawal symptoms.

OxyContin Withdrawal Symptoms

A woman holding OxyContin on her hand

Although withdrawing from opioid medications like OxyContin is not typically life-threatening, it can cause severe discomfort and distressing symptoms. 

Abruptly stopping OxyContin use can result in serious opioid withdrawal symptoms, unmanageable pain, and even thoughts of suicide [4].

Oxycodone withdrawal can cause a range of symptoms, such as:

8 Behavioral Symptoms

  • Avoiding social situations
  • Strained relationships
  • Slurring of speech
  • Loss of interest in previously enjoyed activities
  • Continued use of OxyContin despite negative consequences
  • Doctor shopping to obtain multiple prescriptions
  • Prioritizing OxyContin use over daily responsibilities
  • Consistent OxyContin use

9 Physical Symptoms

  • A man experiencing physical symptoms due to OxyContin withdrawalRestlessness or slowed movements
  • Drowsiness
  • Constricted pupils
  • Cognitive symptoms:
  • Memory impairment
  • Persistent cravings for OxyContin
  • Impaired judgment
  • Difficulty concentrating
  • Respiratory depression

3 Psychosocial Symptoms

  • Apathy
  • Dysphoria or feeling uneasy
  • Euphoria

The American Psychological Association states that people with opioid use disorder are more likely to experience symptoms of other mental health conditions [5].

Related Articles:

Some of these co-occurring disorders may include:

  • Other substance use disorders
  • Posttraumatic stress disorder (PTSD)
  • Persistent depressive disorder
  • Major depressive disorder

OxyContin Withdrawal Timeline

The time it takes to withdraw from opioids varies depending on whether the opioids are short-acting or long-acting. OxyContin, a long-acting form of oxycodone, causes extended-release opioid effects.

Withdrawal symptoms usually start within 2-4 days after the last dose, reach their highest point after 72-96 hours, and gradually decrease over around 2 weeks [6].

Factors That Impact OxyContin Withdrawal

Stacks of OxyContin tablets

The symptoms of withdrawal can differ from person to person. Different factors can affect how severe and how long your symptoms will last.

The factors include:

  • The amount
  • Duration
  • Type of opioid used
  • Your previous history of withdrawal
  • Your overall health
  • Whether or not you have any medical disorders

OxyContin Withdrawal Treatment

A doctor talking to her patientOxyContin withdrawal can be a challenging experience, but effective treatments are available to help manage the symptoms.

A medical detox is a common approach, where patients are monitored by healthcare professionals while gradually tapering off the drug.

The Substance Abuse and Mental Health Services Administration (SAMHSA) recommends that individuals withdrawing from opioids receive hospitalization or another form of 24-hour medical care due to potential safety risks and intense suffering. 

Withdrawal from opioids can lead to complications such as severe dehydration, uncontrolled pain, worsening of anxiety or underlying cardiac illnesses, or even suicide.

Medical Detox

A patient having a conversation with his doctorMedical detox provides supervision, support, and medication to ensure safety and comfort. Please remember that medical detox is not a complete solution for rehabilitation.

Detox is a necessary process that helps your body achieve a medically stable condition while handling withdrawal symptoms in a secure and nurturing environment. 

Usually, detoxification serves only as the first phase of oxycodone addiction recovery and helps you get ready for substance abuse treatment. A

after completing detox, most people continue their recovery through a formal rehab or treatment program to tackle the root causes of their drug addiction.

Also Read: How Long Does a Drug Detox Take

Addiction Treatment Program

Depending on the severity of the addiction, inpatient or outpatient addiction treatment programs may be recommended. These programs typically use a combination of medication and behavioral therapy to address the root causes of addiction and support recovery.

Detox Drinks

Moreover, people are now turning to detox drinks as a natural and common method to alleviate OxyContin withdrawal symptoms. This is because these drinks are made of ingredients that promote liver function and aid in eliminating toxins from the body.

“Individuals may remain on medications like methadone or buprenorphine during maintenance, and they may also receive naltrexone, an opioid antagonist that blocks the euphoric effects of opioids.”
Stacy Mosel, Substance Abuse Specialist at American Addiction Centers


How Long Does OxyContin Detox Last?

The amount of time OxyContin detox lasts depends on several factors, such as the duration and amount of OxyContin intake and the user’s opioid usage history. OxyContin detox’s most intense phase generally lasts 5 to 10 days.

What Are the Options for OxyContin Recovery?

Options for OxyContin recovery include inpatient and outpatient treatment programs, counseling and therapy, support groups, and medication-assisted treatment. The most effective approach will depend on the individual’s needs and addiction severity.

How Long Does OxyContin Take to Stop The Pain?

The amount of time it takes for OxyContin to stop the pain is not always predictable, as it depends on the individual and their medical condition. OxyContin will begin to reduce the physical pain after about 15 minutes for most people, but some may experience relief within 30 minutes or an hour. 

Do You Need Help Managing OxyContin Withdrawal Symptoms?

Managing withdrawal symptoms is crucial for a successful recovery from addiction. While several products are available in the market, choosing the one that fits your needs and preferences is important.

Detox drinks have emerged as a popular and natural way to help manage the physical withdrawal symptoms of OxyContin.

After researching several products on the market, check out our review of Clear Choice Rescue Drink as one of the most reliable options available. Its unique formula helps to detoxify the body and eliminate toxins, making it an effective solution for individuals looking to manage their symptoms.

If you experience withdrawal symptoms, consider trying Clear Choice Rescue Drink as a part of your recovery plan under the guidance of a healthcare professional.


  1. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/
  2. https://www.deadiversion.usdoj.gov/schedules/
  3. https://www.fda.gov/media/131026/download
  4. https://americanaddictioncenters.org/withdrawal-timelines-treatments/opiate
  5. https://www.psychiatry.org/patients-families/opioid-use-disorder 
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202507/

Leave a Reply

Your email address will not be published. Required fields are marked *